CHES Platform

What is it?

The CHES platform is a specialized software dedicated to the assessment, storage and processing of electronically collected patient-reported outcome data (ePRO). It is a product of the software company ESD – Evaluation Software Development ( and facilitates the use of the PRO measures of the EORTC Quality of Life Group (QLG), their development (phase III and IV studies) and research activities as well as the dissemination of computer adaptive measures (CAT). Furthermore, the CHES platform promotes the use of ePRO in daily clinical routine by providing a versatile tool suitable for health care personnel and patients (online patient portal fostering patient empowerment) alike.

How does it work?

Depending on the purpose of ePRO, the functionalities of the CHES platform cover the administration of questionnaires or CAT, the processing of data and its sophisticated graphical presentation, the monitoring and management of studies by providing electronic case report forms, assessment schedules, remote data assessment and patient portals. Especially CAT requires a reliable and feasible software system for measurement dissemination. The functionalities of the CHES platform include amongst others:

  • The demonstration and administration of the EORTC-QLQ CAT measures. For this purpose, it is possible to try CAT for the EORTC QLQ-C30 scales Physical, Emotional and Social Functioning and Fatigue. After each answer, the item response theory (IRT) score and its confidence interval is displayed. A summary of data is provided after CAT completion.
  • The demonstration and implementation of CHES in daily oncology practice when using EORTC QLQ measures.
  • Questionnaire administration and/or data collection in the framework of EORTC QLQ module development studies.
  • Monitoring features for conducting methodological studies concerning EORTC QLG measures.

All data collected with the CHES platform in EORTC QLG studies are securely and anonymously stored on EORTC servers. Nonetheless, a sophisticated data export tool allows principal investigators as well as collaborators to export their data.

How is it used?

The CHES platform can be used in all common web-browsers and does not require any local software installation. The software complies with the Good clinical practice guidelines (GCP) for electronic data collection.

A master agreement signed by the EORTC Headquarters and the company ESD ensures the free and unrestricted use of the software for QLG members within QLG-funded studies for the duration of the grant period. QLG group members can even make themselves familiar with functionalities designed for the use of ePRO in daily clinical routine.

Participating collaborators receive a unique user name and password for the individual setup of the CHES platform used for the respective study. Depending on previously allocated user rights, users can e.g. enter and edit data, prepare questionnaires for completion, manage studies, collect ePRO and access and/or download files (such as a user manual, troubleshooting handbook, case report forms, etc).

After being entered into the database (by using a Health Level 7 interface to clinical information systems/electronic health records this step can be automated), patients receive a unique user name and password as well, but access a different graphical interface with functionalities which are tailored to data collection and the interests of patients. If a study includes access to a patient portal, patients can be provided with their own ePRO scores and online content, which takes their individual situation into account (e.g. a patient with high scores of sleeping disturbances can be provided with educational material regarding sleep hygiene).


Access the CHES Platform