Comparison of the EORTC QLU-C10D

Principal investigator(s)
Eva Maria Gamper
Medical University of Innsbruck Department for Psychiatry, Psychotherapy, and Psychosomatic Medicine
Innsbruck, Austria

Project summary

The QLU-C10D is a newly developed, cancer-specific multi-attribute utility instrument (MAUI) which has been included in the EORTC assessment system and can be used for health economic evaluations in cost-utility analyses (CUA). The most commonly used utility instruments are generic, i.e. cover overal aspects of functioning only. The QLU-C10D is based on the QLQ-C30 and includes 10 of its 15 domains. Therefore, it is considered to capture symtpoms and functioning aspects specific to cancer patients and to be more sensitive in this patient group.

The present study aims at assessing the relative validity of the QLU-C10D in cancer patients compared to the most widely used generic utilty instruments, such as the EQ-5D and the SF-6D. Furthermore, a manual for the use of the QLU-C10D in CUAs will be developed.


A systematic literature review to search for existing studies including the questionnaires of interest (QLQ-C30 + a generic utility instrument) has been completed.

Future plans

Extraction of existing trial data – 8/2018

Publication of first results – 9/2018

Completion prospective patient data collection – 6/2019

Draft version of preliminary user manual 12/2018

For patients

The QLU-C10D is a kind of questionnaire, developed to capture cancer patients’ quality of life and to relate it to survival time and costs of treatment in health economic studies. The study investigates whether the QLU-C10D is able to capture cancer patients’ quality of life issues more precisely than generic questionnaires which were not designed specifically for cancer patients.